|Rapporto Attività 2005|
The Mario Negri Institute for Pharmacological Research was established as a non-profit foundation in 1963. Mario Negri, a farsighted philanthropist with interests in several industrial activities, specified in his will that Silvio Garattini, M.D. - then a young professor of chemotherapy and pharmacology at the University of Milan and leader of a small research group - was to establish an institute of pharmacology, for research and education in biomedicine. Now, thirty-five years later, besides the original Institute in Milan, there are other research centers in Bergamo and S. Maria Imbaro, near Chieti, in Southern Italy. Research spans from molecular biology to biochemistry, analytical chemistry and pharmacology to large controlled clinical trials, conducted in cooperation with clinical centers in Italy and abroad. The 22 initial founders have grown to a staff of over 800, half of whom university graduates. About 2,000 young people have received research training at different levels and over 400 foreign scientists from 50 countries have completed stages at the Institute. Over 5,000 scientific papers, published in international journals, have reported experimental, clinical, epidemiological studies in the field of cancer, immunology, mental illness, cardiovascular and renal diseases, mother and child health, neuropharmacology and neuroendocrinology, and age-related illnesses.
The Department of Cardiovascular Research has been established as the natural evolution of a growing collaboration of three Laboratories:
The areas of interest of the Department include the experimental, clinical, epidemiological aspects of acute myocardial infarction, cardiac failure, ventricular arrhythmias, peripheral arteriopathy and venous thromboembolic disease, as well as the clinical and epidemiological investigation of cardiovascular prevention, hypertension and stroke. Following the successful experience of the GISSI-trials (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto), the activation of large collaborative networks in the setting of the National Health Service hospitals and in general practice has become a key characteristics of the Department, which can now rely on the permanent collaboration of over 300 clinical groups and of several hundred general practitioners. Over the years, firm links have also been established with international leading research groups.